recombinant human ox40l Search Results


recombinant human ox40l  (BPS Bioscience)
90
BPS Bioscience recombinant human ox40l
Novel VALO-D102 oncolytic adenovirus produces high levels of biologically active human CD40 ligand (CD40L) and <t>OX40</t> <t>ligand</t> <t>(OX40L)</t> (A) Schematic representation of genetic modifications in VALO-D102. The virus has a 24-base pair deletion in E1A; the CR1-alpha and gp19K genes in the E3A region have been replaced with human OX40L and CD40L genes; the 14.7K gene in the E3B region has been deleted; and finally, the adenovirus 5 knob domain has been replaced with the knob domain from adenovirus serotype 3. (B) A549 cells were infected with VALO-D102 at a MOI of 10. 72 h postinfection, supernatant was collected and added to a culture of Ramos-Blue reporter cells, and CD40 receptor activation by functional virus-produced CD40L was measured. (C) A549 cells were infected with VALO-D102 at a MOI of 10. 48 h postinfection, HEK293-OX40/NF-κB reporter cells were added to the infected A549 cells for 6 h, and OX40 activation by virus-expressed, functional membrane-bound OX40L was measured.
Recombinant Human Ox40l, supplied by BPS Bioscience, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/recombinant human ox40l/product/BPS Bioscience
Average 90 stars, based on 1 article reviews
recombinant human ox40l - by Bioz Stars, 2026-02
90/100 stars
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human ox40 ox 0-h5224  (ACROBiosystems)
90
ACROBiosystems human ox40 ox 0-h5224
Novel VALO-D102 oncolytic adenovirus produces high levels of biologically active human CD40 ligand (CD40L) and <t>OX40</t> <t>ligand</t> <t>(OX40L)</t> (A) Schematic representation of genetic modifications in VALO-D102. The virus has a 24-base pair deletion in E1A; the CR1-alpha and gp19K genes in the E3A region have been replaced with human OX40L and CD40L genes; the 14.7K gene in the E3B region has been deleted; and finally, the adenovirus 5 knob domain has been replaced with the knob domain from adenovirus serotype 3. (B) A549 cells were infected with VALO-D102 at a MOI of 10. 72 h postinfection, supernatant was collected and added to a culture of Ramos-Blue reporter cells, and CD40 receptor activation by functional virus-produced CD40L was measured. (C) A549 cells were infected with VALO-D102 at a MOI of 10. 48 h postinfection, HEK293-OX40/NF-κB reporter cells were added to the infected A549 cells for 6 h, and OX40 activation by virus-expressed, functional membrane-bound OX40L was measured.
Human Ox40 Ox 0 H5224, supplied by ACROBiosystems, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/human ox40 ox 0-h5224/product/ACROBiosystems
Average 90 stars, based on 1 article reviews
human ox40 ox 0-h5224 - by Bioz Stars, 2026-02
90/100 stars
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human ox40l recombinant protein elabscience pksh032843  (Elabscience Biotechnology)
90
Elabscience Biotechnology human ox40l recombinant protein elabscience pksh032843
Novel VALO-D102 oncolytic adenovirus produces high levels of biologically active human CD40 ligand (CD40L) and <t>OX40</t> <t>ligand</t> <t>(OX40L)</t> (A) Schematic representation of genetic modifications in VALO-D102. The virus has a 24-base pair deletion in E1A; the CR1-alpha and gp19K genes in the E3A region have been replaced with human OX40L and CD40L genes; the 14.7K gene in the E3B region has been deleted; and finally, the adenovirus 5 knob domain has been replaced with the knob domain from adenovirus serotype 3. (B) A549 cells were infected with VALO-D102 at a MOI of 10. 72 h postinfection, supernatant was collected and added to a culture of Ramos-Blue reporter cells, and CD40 receptor activation by functional virus-produced CD40L was measured. (C) A549 cells were infected with VALO-D102 at a MOI of 10. 48 h postinfection, HEK293-OX40/NF-κB reporter cells were added to the infected A549 cells for 6 h, and OX40 activation by virus-expressed, functional membrane-bound OX40L was measured.
Human Ox40l Recombinant Protein Elabscience Pksh032843, supplied by Elabscience Biotechnology, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/human ox40l recombinant protein elabscience pksh032843/product/Elabscience Biotechnology
Average 90 stars, based on 1 article reviews
human ox40l recombinant protein elabscience pksh032843 - by Bioz Stars, 2026-02
90/100 stars
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recombinant human ox40 ligand protein  (imaGenes GmbH)
90
imaGenes GmbH recombinant human ox40 ligand protein
Novel VALO-D102 oncolytic adenovirus produces high levels of biologically active human CD40 ligand (CD40L) and <t>OX40</t> <t>ligand</t> <t>(OX40L)</t> (A) Schematic representation of genetic modifications in VALO-D102. The virus has a 24-base pair deletion in E1A; the CR1-alpha and gp19K genes in the E3A region have been replaced with human OX40L and CD40L genes; the 14.7K gene in the E3B region has been deleted; and finally, the adenovirus 5 knob domain has been replaced with the knob domain from adenovirus serotype 3. (B) A549 cells were infected with VALO-D102 at a MOI of 10. 72 h postinfection, supernatant was collected and added to a culture of Ramos-Blue reporter cells, and CD40 receptor activation by functional virus-produced CD40L was measured. (C) A549 cells were infected with VALO-D102 at a MOI of 10. 48 h postinfection, HEK293-OX40/NF-κB reporter cells were added to the infected A549 cells for 6 h, and OX40 activation by virus-expressed, functional membrane-bound OX40L was measured.
Recombinant Human Ox40 Ligand Protein, supplied by imaGenes GmbH, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/recombinant human ox40 ligand protein/product/imaGenes GmbH
Average 90 stars, based on 1 article reviews
recombinant human ox40 ligand protein - by Bioz Stars, 2026-02
90/100 stars
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recombinant human ox40l-fc  (PeproTech)
90
PeproTech recombinant human ox40l-fc
Novel VALO-D102 oncolytic adenovirus produces high levels of biologically active human CD40 ligand (CD40L) and <t>OX40</t> <t>ligand</t> <t>(OX40L)</t> (A) Schematic representation of genetic modifications in VALO-D102. The virus has a 24-base pair deletion in E1A; the CR1-alpha and gp19K genes in the E3A region have been replaced with human OX40L and CD40L genes; the 14.7K gene in the E3B region has been deleted; and finally, the adenovirus 5 knob domain has been replaced with the knob domain from adenovirus serotype 3. (B) A549 cells were infected with VALO-D102 at a MOI of 10. 72 h postinfection, supernatant was collected and added to a culture of Ramos-Blue reporter cells, and CD40 receptor activation by functional virus-produced CD40L was measured. (C) A549 cells were infected with VALO-D102 at a MOI of 10. 48 h postinfection, HEK293-OX40/NF-κB reporter cells were added to the infected A549 cells for 6 h, and OX40 activation by virus-expressed, functional membrane-bound OX40L was measured.
Recombinant Human Ox40l Fc, supplied by PeproTech, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/recombinant human ox40l-fc/product/PeproTech
Average 90 stars, based on 1 article reviews
recombinant human ox40l-fc - by Bioz Stars, 2026-02
90/100 stars
  Buy from Supplier

Image Search Results


Novel VALO-D102 oncolytic adenovirus produces high levels of biologically active human CD40 ligand (CD40L) and OX40 ligand (OX40L) (A) Schematic representation of genetic modifications in VALO-D102. The virus has a 24-base pair deletion in E1A; the CR1-alpha and gp19K genes in the E3A region have been replaced with human OX40L and CD40L genes; the 14.7K gene in the E3B region has been deleted; and finally, the adenovirus 5 knob domain has been replaced with the knob domain from adenovirus serotype 3. (B) A549 cells were infected with VALO-D102 at a MOI of 10. 72 h postinfection, supernatant was collected and added to a culture of Ramos-Blue reporter cells, and CD40 receptor activation by functional virus-produced CD40L was measured. (C) A549 cells were infected with VALO-D102 at a MOI of 10. 48 h postinfection, HEK293-OX40/NF-κB reporter cells were added to the infected A549 cells for 6 h, and OX40 activation by virus-expressed, functional membrane-bound OX40L was measured.

Journal: Molecular Therapy Oncolytics

Article Title: Characterization of a novel OX40 ligand and CD40 ligand-expressing oncolytic adenovirus used in the PeptiCRAd cancer vaccine platform

doi: 10.1016/j.omto.2021.02.006

Figure Lengend Snippet: Novel VALO-D102 oncolytic adenovirus produces high levels of biologically active human CD40 ligand (CD40L) and OX40 ligand (OX40L) (A) Schematic representation of genetic modifications in VALO-D102. The virus has a 24-base pair deletion in E1A; the CR1-alpha and gp19K genes in the E3A region have been replaced with human OX40L and CD40L genes; the 14.7K gene in the E3B region has been deleted; and finally, the adenovirus 5 knob domain has been replaced with the knob domain from adenovirus serotype 3. (B) A549 cells were infected with VALO-D102 at a MOI of 10. 72 h postinfection, supernatant was collected and added to a culture of Ramos-Blue reporter cells, and CD40 receptor activation by functional virus-produced CD40L was measured. (C) A549 cells were infected with VALO-D102 at a MOI of 10. 48 h postinfection, HEK293-OX40/NF-κB reporter cells were added to the infected A549 cells for 6 h, and OX40 activation by virus-expressed, functional membrane-bound OX40L was measured.

Article Snippet: Recombinant human OX40L (BPS Bioscience) was used as a standard.

Techniques: Infection, Activation Assay, Functional Assay, Produced

Virus-encoded OX40L and CD40L improve anti-tumor efficacy and induce robust infiltration of tumor-specific CD8 + T cells into the tumor in a syngeneic mouse model of B16.OVA melanoma (A) 1 × 10 9 VP of PeptiCRAd Ad5/3-D24-OVA or PeptiCRAd VALO-mD901-OVA was given intratumorally 6, 8, and 20 days post-tumor implantation. Average tumor growth curves for all treatment groups are shown. (B) Immunological analysis of tumors and tumor-draining lymph nodes of treated mice. Lymph nodes from all mice from each treatment group were pooled in order to get enough cells for the flow cytometric analysis. The number of mice in the mock group was 7 and in both PeptiCRAd groups, was 10. Statistical analysis was performed with one-way ANOVA. ∗p < 0.05, ∗∗p < 0.01.

Journal: Molecular Therapy Oncolytics

Article Title: Characterization of a novel OX40 ligand and CD40 ligand-expressing oncolytic adenovirus used in the PeptiCRAd cancer vaccine platform

doi: 10.1016/j.omto.2021.02.006

Figure Lengend Snippet: Virus-encoded OX40L and CD40L improve anti-tumor efficacy and induce robust infiltration of tumor-specific CD8 + T cells into the tumor in a syngeneic mouse model of B16.OVA melanoma (A) 1 × 10 9 VP of PeptiCRAd Ad5/3-D24-OVA or PeptiCRAd VALO-mD901-OVA was given intratumorally 6, 8, and 20 days post-tumor implantation. Average tumor growth curves for all treatment groups are shown. (B) Immunological analysis of tumors and tumor-draining lymph nodes of treated mice. Lymph nodes from all mice from each treatment group were pooled in order to get enough cells for the flow cytometric analysis. The number of mice in the mock group was 7 and in both PeptiCRAd groups, was 10. Statistical analysis was performed with one-way ANOVA. ∗p < 0.05, ∗∗p < 0.01.

Article Snippet: Recombinant human OX40L (BPS Bioscience) was used as a standard.

Techniques: Tumor Implantation